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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
23.64
Human Site:
S925
Identified Species:
40
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S925
Y
H
A
G
L
S
D
S
A
R
D
E
V
Q
Q
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S925
Y
H
A
G
L
S
D
S
A
R
D
E
V
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S924
Y
H
A
G
L
S
D
S
A
R
D
E
V
Q
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
S933
Y
H
A
G
L
S
D
S
A
R
D
E
V
Q
H
Rat
Rattus norvegicus
Q6AYJ1
621
69624
G155
L
M
V
L
Q
Q
L
G
I
S
A
T
M
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
D325
G
M
G
I
D
K
P
D
V
R
Y
V
I
H
A
Chicken
Gallus gallus
Q9I920
1142
126164
T676
G
C
Q
V
I
C
A
T
I
A
F
G
M
G
I
Frog
Xenopus laevis
Q9DEY9
1364
152305
S877
Y
H
A
G
L
A
D
S
N
R
D
Y
V
Q
H
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
Y795
I
S
A
L
Q
N
L
Y
E
R
G
L
L
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
T995
Y
H
A
G
L
T
D
T
D
R
E
S
R
Q
K
Honey Bee
Apis mellifera
XP_396209
961
109321
V495
P
A
L
K
L
L
Y
V
T
P
E
K
I
S
A
Nematode Worm
Caenorhab. elegans
O18017
988
110641
V522
W
I
A
N
K
F
D
V
I
C
A
T
I
A
F
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
S919
I
D
E
A
H
C
V
S
Q
W
G
H
D
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
D937
Y
H
A
G
M
E
P
D
E
R
L
S
V
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
0
N.A.
6.6
0
73.3
13.3
N.A.
53.3
6.6
13.3
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
6.6
N.A.
13.3
20
80
33.3
N.A.
80
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
65
8
0
8
8
0
29
8
15
0
0
15
15
% A
% Cys:
0
8
0
0
0
15
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
50
15
8
0
36
0
8
0
0
% D
% Glu:
0
0
8
0
0
8
0
0
15
0
15
29
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
8
% F
% Gly:
15
0
8
50
0
0
0
8
0
0
15
8
0
8
0
% G
% His:
0
50
0
0
8
0
0
0
0
0
0
8
0
8
15
% H
% Ile:
15
8
0
8
8
0
0
0
22
0
0
0
22
0
8
% I
% Lys:
0
0
0
8
8
8
0
0
0
0
0
8
0
0
15
% K
% Leu:
8
0
8
15
50
8
15
0
0
0
8
8
8
8
0
% L
% Met:
0
15
0
0
8
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
15
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
8
0
15
8
0
0
8
0
0
0
0
50
22
% Q
% Arg:
0
0
0
0
0
0
0
0
0
65
0
0
8
0
15
% R
% Ser:
0
8
0
0
0
29
0
43
0
8
0
15
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
15
8
0
0
15
0
0
0
% T
% Val:
0
0
8
8
0
0
8
15
8
0
0
8
43
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
50
0
0
0
0
0
8
8
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _